A PROTOCOL FOR ASSESSING THE THERAPEUTIC BENEFITS OF GUDSARSAPA TAILA AND HARIDRADI CHURNA IN TAMAKA SHWASA (BRONCHIAL ASTHMA): A COMPARATIVE APPROACH.

Background: Tamaka Shwasa (Bronchial Asthma) is a chronic respiratory disorder characterized by recurrent episodes of breathlessness, wheezing, and airway obstruction. Current conventional treatments involve bronchodilators, corticosteroids, and immunosuppressive agents, which may lead to adverse effects with long-term use. Ayurveda mentions Gud-Sarsapa Taila and Haridradi Churna as effective remedies for Tamaka Shwasa. This study aims to evaluate and compare the clinical efficacy of these formulations in the management of Tamaka Shwasa. Objectives: 1. To assess and compare the effectiveness of Gud-Sarsapa Taila and Haridradi Churna in managing Tamaka Shwasa. 2. To evaluate changes in absolute eosinophil count (AEC) and serum IgE levels post-intervention. 3. To determine the symptomatic relief in breathlessness using the modified Medical Research Council (mMRC) Dyspnea Scale. Material and Methods: A randomized, single-center, interventional, comparative clinical trial will be conducted on 100 participants diagnosed with Tamaka Shwasa. Patients will be divided into two groups: Group A: Gud-Sarsapa Taila administration. Group B: Haridradi Churna administration. The study duration will be 21 days, with follow-ups on the 7th, 14th, and 21st days. Primary outcomes include changes in breathlessness severity (mMRC Dyspnea Scale), AEC, and serum IgE levels. Secondary outcomes include symptom relief and need for emergency medication. Results: Significant reduction in breathlessness severity in both groups. Reduction in serum IgE levels and AEC, indicating immunomodulatory effects. Gud-Sarsapa Taila and Haridradi Churna will provide symptomatic relief, with possible comparative differences in efficacy. No major adverse effects anticipated due to the natural origin of the formulations. Conclusion: The study is expected to demonstrate the efficacy of GudSarsapa Taila and Haridradi Churna in managing Tamaka Shwasa while providing an alternative treatment option with minimal adverse effects. The findings may contribute to integrating Ayurvedic management into the treatment of Bronchial Asthma. [ABSTRACT FROM AUTHOR]