Penile carcinoma: A retrospective analysis of 93 patients at a tertiary care center in Jakarta, Indonesia.
Published In: International Journal of Urology, 2024, v. 31, n. 7. P. 764 1 of 3
Database: Academic Search Ultimate 2 of 3
Authored By: Manurung, Mega Anara; Umbas, Rainy; Hamid, Agus Rizal A. H.; Mochtar, Chaidir Arif 3 of 3
Abstract
Objectives: Penile carcinoma (PC) is a rare disease with considerable physical and psychological impact. To date, there is no data regarding PC prevalence and characteristics in Indonesia. This study aimed to analyze the characteristics of patients with PC in Indonesia and determine cumulative survival rates and time to disease progression. Methods: This was a retrospective study of all patients diagnosed with PC at Cipto Mangunkusumo General Hospital from 1995 to 2014, with a minimum of 1 year follow‐up. The outcomes of the study were cumulative survival rates and time‐to‐disease progression. Results: Ninety‐three subjects were recruited, with a mean age of 49.44 ± 13.62. Inguinal lymph node dissection (ILND) was performed in 49 (53%) patients. The mean survival in the ILND group was better compared to the non‐ILND group (80.7 months vs. 67.1 months; p = 0.032). Time‐to‐progression in the ILND group was significantly longer than in the non‐ILND group (71.7 months vs. 54.3 months; p = 0.022). No significant difference in survival between the total and partial penectomy (PP) groups was observed (p = 0.701). Time‐to‐progression in total penectomy (TP) was significantly longer than in PP (68 months vs. 56.0 months; p = 0.023). In Cox‐regression analysis, after adjustment of other variables, history of ILND, higher stage of cancer, and older age were found to affect the survival of patients. Conclusion: ILND in PC led to better survival and reduced disease progression. The type of penectomy is only associated with progression but not survival. TP had a longer time to disease progression compared to PP. [ABSTRACT FROM AUTHOR]
Additional Information
- Source:International Journal of Urology. 2024/07, Vol. 31, Issue 7, p764
- Document Type:Article
- Subject Area:Geography and Cartography
- Publication Date:2024
- ISSN:0919-8172
- DOI:10.1111/iju.15462
- Accession Number:178296485
- Copyright Statement:Copyright of International Journal of Urology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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